If you're interested in gene-gene and gene-environment interaction (and who wouldn't be?), then you should check out the Epistasis Blog. Our friend and colleague Jason Moore at Dartmouth Medical School has maintained compgen.blogspot.com since 2005 writing about epistasis, computational genetics, and related topics. I've personally stumbled upon several interesting papers mentioned here that I may have otherwise missed.
Also, be sure to check out other posts in GGD's Noteworthy Blogs series!
Jason Moore's Epistasis Blog (compgen.blogspot.com)